Background:
Autogenous platelet rich plasma (PRP) has found its many applications to medicine, and orthopaedics and aesthetic medicine in particular. It is becoming more and more popular in dentistry. PRP is effectively used as an adjunct in periodontology, implantology, as well as in maxillofacial surgery.

Aim:
To present current knowledge on the possibilities of using platelet-rich plasma in medicine, with particular emphasis on aesthetic medicine and dentistry. The authors focused on an approximation of the methods, method of acquiring the preparation, the equipment used and the mechanism of PRP operation.

Material and methods:
A systematic, comprehensive review of scientific publications published in 2008-2018 in the PubMed database has been carried out and concerned the acquisition and use of platelet-rich plasma in medicine with particular emphasis on aesthetic medicine and dentistry.

Results:
Platelet rich plasma contains many biologically active substances that affect cell proliferation and regeneration. Thanks to their properties, it accelerates the reconstruction of tissues, reduces swelling and pain during dental treatment, determines faster osseointegration in surgical treatment, stimulates healing of scars and chronic wounds, also smoothes wrinkles, nourishes and moisturizes the skin.

Conclusions:
The range of diseases in which PRP can be administered is very wide. As a method of regenerative therapy, it gives hope on many levels. It is now considered the best and most effective method of non-surgical medicine.