Implantological treatment in the maxilla in the case of considerable loss of the prosthetic base is difficult. In extreme cases, atrophy in the maxilla is extensive, which excludes the rehabilitation of the stomatognathic system with removable or implant-supported dentures. Zygomatic implants enable anchorage of the permanent dentures in the upper dental arch if there is an insufficient amount of bone. Additional regenerative procedures are not necessary, which significantly shortens the treatment time and the number of operations to perform. The aim of the study was to present the implantological treatment using zygomatic implants in patients with extreme maxillary atrophy. Zygomatic implants can present an alternative for patients with extreme bone loss. The survival rate of such implants is high, with a low level of prosthetic and maxillary sinus complications.