Treatment of head and neck cancer involves the use of surgical methods as well as radiotherapy and/or chemotherapy. In adolescents, this model of treatment designed for adult patients can be modified. Typically, massive irradiation of the head and neck area is the main therapeutic modality. This approach, however, contributes to the formation of a number of anatomical and functional deficits within the prosthetic area and the stomatognathic system, which is still in the phase of intensive development of the young body. These deficits effectively reduce the prognosis of these patients for successful prosthetic rehabilitation. The development of methods of treatment with the use of intraosseous implants creates the opportunity to perform prosthetic treatment often in extremely difficult conditions of the prosthetic base, which found its application in postsurgical treatment of patients. This paper presents a clinical case of a patient diagnosed at the age of 2 years with rhabdomyosarcoma in the region of the midface. The oncological treatment arrested the development of the lower part of the face with subsequent oligodontia. At the age of 14 years the patient underwent implantoprosthetic rehabilitation within the mandible: two intraosseous implants were inserted in the mental area to support the lower complete OVD prosthesis. In the next stage of treatment, the decision was made to remove maxillary teeth with undeveloped roots. After bony tissue in the maxilla was remodelled, implantoprosthetic treatment was performed. Four intraosseous implants were inserted into the bone of the alveolar ridge using the Nobel Guide system and a stereolithic surgical template. The patient very quickly adapter to the prosthetic restorations in the form of a complete lower OVD prosthesis and upper OVD framework denture. The patient expressed satisfaction with a definite increase in the quality of daily life and comfort in dentures use.