Introduction. The choice of a specific prosthetic cement should be made on the basis of clinical conditions, the type of prosthetic restoration as well as through the knowledge of the properties of prosthetic cements. The emergence of new cements based on resin matrix (adhesive and self-adhesive) of a different composition and binding mechanism in recent years tends to compare the properties of the above-mentioned cements. Aim of the study. Comaparative evaluation of the mechanical properties of resin. Materials and methods. The following materials were selected for the tests: NX3 and Maxcem Elite Chroma (Kerr), Variolink Esthetic DC and Multilink Automix, SpeedCEM Plus (Ivoclar Vivadent), Cement-It and Breez (Jenerix Penrton), Bistite II DC and Estecem (Tokuyama), Panavia 2.0 and Panavia SA Cement Plus (Kuraray), G-CEM LinkAce (GC), RelyX U200 (3M ESPE),SmartCem 2, Calibra Ceram, Calibra Universal (Dentsply Sirona). Vickers hardness and diametral tensile strength (DTS) of the materials were determined. Results. There were no significant differences in the strength (DTS) of individual cements. It have been found significant differences in the hardness of cements: the highest values were noted for Maxcem Elite Chroma (self-adhesive), Cement- It (composite) and Multilink Automix (adhesive), and the lowest for Variolink Esthetic DC (composite). Conclusions. Resin, self-adhesive and self-etching cements show different hardness with comparable strength.