Introduction:
In the era of an ageing society, despite popularization and increased availability of implantoprosthetic treatment, for numerous patients dental adhesives are an essential element of the successful use of dentures. These materials are commonly used to increase retention and stabilisation, as well as improve the quality of use of removable dentures. Adhesives, as generally available, should be biocompatible, and yet reports indicate possible cytotoxic effects on cells of the oral mucosa. It is difficult to identify the specific ingredients responsible for their hazardous properties, due to the fact that the exact composition of these products is restricted information.

Aim of the study:
To systematize the available knowledge of the biological properties of denture adhesive products and to present their influence on the cells of the oral mucosa.

Material and methods:
A review of the literature using the PubMed and Google Scholar databases was performed.

Results:
The analysis of reports in the literature showed a variety of results regarding the studies on the effects of dental adhesives on fibroblasts of the oral mucosa. Basic assumptions have been presented, and the noticed differences indicated.